ISSN: 1305-385X
Hakkında: Özel sayılar şeklinde yayınlanır.
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Imaging Modalities In Autosomal Dominant Polycystic Kidney Disease
Dr. Ensar YEKELERa
aRadiodiagnostik AD, İstanbul Üniversitesi İstanbul Tıp Fakültesi, İSTANBUL
Autosomal dominant polycystic kidney disease is one of the most common hereditary disorders. In addition to kidney involvement, liver, cardiovascular, gastrointestinal and musculoskeletal involvements can be seen. Ultrasonography is the first modality of choice in diagnosing and follow-up of renal and hepatic involvements which appear as cystic lesions. Unenhanced CT is preferred in detection of calcified cysts and urinary calculi. Hemorrhagic cysts are better demonstrated by MR imaging with higher contrast resolution than CT. Either CT or MR can be used in detection of associated renal tumors and their invasion to the adjacent structures. It can be difficult to evaluate hepatic vascularities by Doppler ultrasonography in the presence of massive hepatic involvement. Therefore, CT or MR angiography is preferred to evaluate the hepatic vascularities in that case. Intracranial aneurysms are most important component of the extrarenal involvement. Although digital subtraction angiography is gold-standard modality in diagnosis of cerebral aneurysms, the invasiveness and possibility of complications due to the procedure are disadvantages. Hence, MR angiography is modality of choice in diagnosis and follow-up of intracranial aneurysms. In MR incompatible patients, CT angiography can be used to noninvasively diagnose the cerebral aneurysms.Keywords: Autosomal dominant polycystic kidney disease, imagingTurkiye Klinikleri J Int Med Sci 2005, 1(4):29-34
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