ISSN: 1305-385X
Hakkında: Özel sayılar şeklinde yayınlanır.
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Neurologic Dysfunction In Chronic Renal Failure
Dr. Ayhan DOĞUKANa
aNefroloji BD, Fırat Üniversitesi Tıp Fakültesi, ELAZIĞ
Neurologic dysfunction induced by uremia commonly occurs and contributes largely to the morbidity and mortality in patients with chronic renal failure. Despite continuous therapeutic advances, many neurological complications of uremia, like uremic encephalopathy, neuropathy and myopathy fail to fully respond to dialysis. Uremic encephalopathy is characterized by clinical signs of depressed brain function coexisting with excitation, often in the form of generalized epileptic seizures. Peripheral neuropathy is common and is characterized by ascending sensory and motor dysfunction. The treatment of renal failure also may lead to the development of neurologic abnormalities in the form of dialysis disequilibrium characterized by headache, nausea, irritability that may progress to seizures, coma, and death. I address briefly the clinical, pathophysiological and therapeutical aspects of neurologic complications in uremia.Keywords: Neuropathy, chronic renal failureTurkiye Klinikleri J Int Med Sci 2005, 1(21):28-32
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