ISSN: 1305-385X
Hakkında: Özel sayılar şeklinde yayınlanır.
|
|
|
Diabetic Nephropathy And Hypertension
Dr. Şükrü SİNDEL,a Dr. Kadriye ALTOK REİSa
aNefroloji BD, Gazi Üniversitesi Tıp Fakültesi, ANKARA
Diabetes has become the most common single cause of end-stage renal disease (ESRD) in the U.S. and Europe. About 20-30% of patients with type 1 or type 2 diabetes develop evidence of nephropathy, but in type 2 diabetes, a considerably smaller fraction of these progress to ESRD. However, because of the much greater prevalence of type 2 diabetes, such patients constitute over half of those diabetic patients currently starting on dialysis. Hypertension (defined as a blood pressure ≥ 140/90 mmHg) is an extremely common comorbid condition in diabetes, affecting ~20-60% of patients with diabetes, depending on obesity, ethnicity, and age. Hypertension substantially increases the risk of both macrovascular and microvascular complications, including stroke, coronary artery disease, peripheral vascular disease, retinopathy, nephropathy, and possibly neuropathy. In recent years, adequate data from well-designed randomized clinical trials have demonstrated the effectiveness of aggressive treatment of hypertension in reducing both types of diabetic complications.Keywords: Diabetes mellitus, hypertension, nephropathyTurkiye Klinikleri J Int Med Sci 2005, 1(38):53-56
|
|
|
|
|
