ISSN: 1305-385X Hakkında: Özel sayılar şeklinde yayınlanır.
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Renovascular Hypertension In Adults
Dr. Kadriye ALTOK REİS,a Dr. Şükrü SİNDELa
aNefroloji BD, Gazi Üniversitesi Tıp Fakültesi, ANKARA Renovascular disease (RAS) is a common, but complex disorder, the most common causes of which are fibromuscular dysplasia and atherosclerosis. The high prevalence of RAS in patients with coronary and lower extremity vascular disease has been well established. Fibromuscular dysplasia in young females and atherosclerosis in patients over the age of 55 are the most common causes. Duplex ultrasonography and magnetic resonance angiography have largely replaced captopril scanning for RAS screening. However, renal angiography still remains the gold standard to diagnose RAS. Progressive renovascular disease during medical therapy can produce refractory hypertension, congestive heart failure, and renal failure with tubulointerstitial fibrosis. Treatment options include medical therapy, angioplasty, and surgery. In general, patients with a stenosis greater than 50%, a translesional systolic pressure gradient greater than 15 mm Hg, and difficult-to-control hypertension and/or worsening renal insufficiency are candidates for renal revascularization.Keywords: Atherosclerosis, hypertension, renal artery stenosisTurkiye Klinikleri J Int Med Sci 2005, 1(38):61-64
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