ISSN: 1305-385X Hakkında: Özel sayılar şeklinde yayınlanır.
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Peritoneal Dialysis: Noninfectious Complications
Dr. Rengin ELSÜRER,a Dr. Siren SEZEa
aNefroloji BD, Başkent Üniversitesi Tıp Fakültesi, ANKARA Peritoneal dialysis (PD), which has been employed in the treatment of acute renal failure in 1950’s and 1960’s, depends on the principle of solute and fluid exchange between peritoneal capillary blood and intraabdominal dialysate fluid. Following the introduction of continuous ambulatory peritoneal dialysis in 1976, the practice of PD became more frequent. At present, PD is the renal replacement therapy of choice in 12-15% of end stage renal disease patients and there are more than 130 000 PD patients throughout the world. Among the advantages of PD are preservation of residual renal function, improved quality of life, facilitation of anemia control and reduced cost. Patients may have to switch to hemodialysis due to complications of PD; namely peritonitis, catheter exit site infection, catheter malfunction, inadequate clearence and ultrafiltration. The frequency of PD practice peaked during 1990’s; however, beginning from 2000’s, due to complications encountered during the treatment, PD is being preferred as the renal replacement therapy in gradually fewer patients. The complications of PD are classifed as infectious or noninfectious. Noninfectious complications of PD are discussed in this review. Despite various complications seen during the treatment, with the advances in the alternative treatment modalities (e.g. biocompatible dialysis solutions, automated PD alternatives) PD remains to be a promising renal replacement therapy modality.Keywords: Peritoneal dialysis, complication, noninfectiousTurkiye Klinikleri J Int Med Sci 2006, 2(4):41-47
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